Saturday, March 31, 2012

Top Google+ trends: Dell stops selling smartphones in US, Apple posters in China

[ [ [['A JetBlue flight from New York to Las Vegas', 3]], 'http://yhoo.it/GV9zpj', '[Related: View photos of the JetBlue plane in Amarillo]', ' ', '630', ' ', ' ', ], [ [['Afghan security forces and police killed three', 3]], 'http://yhoo.it/H9BcJE', '[Related: Bales\' wife on his alleged shooting: \'He would not do that\']', ' ', '630', ' ', ' ', ], [ [['looking for fireworks between the opposing camps', 16]], 'http://yhoo.it/GSvEsj', '[RELATED:\?It?s going to be a circus\?: Activists begin protests outside Supreme Court]', ' ', '630', ' ', ' ', ], [ [['entirely respectable way to put off the searing constitutional controversy', 8]], 'http://yhoo.it/GE6jSh', '[RELATED: Obama\?s health care law passed 2 years ago, but where are we now\?]', ' ', '630', ' ', ' ', ], [ [['Witnesses said the gunman pulled up on a black scooter', 7]], 'http://yhoo.it/GzwOIW', '[Related: New York police tighten security at Jewish sites]', ' ', '630', ' ', ' ', ], [ [['test Zimmerman for alcohol or drugs', 11]], 'http://yhoo.it/Gzn6VF', '[Related: White House says Trayvon Martin is local issue]', ' ', '630', ' ', ' ', ], [ [['Trayvon Martin decked the Neighborhood', 7]], 'http://yhoo.it/GUovUP', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/2/61/261d2c36bccf0971c2734a4d4398aa5a.jpeg', '512', ' ', 'AP/David Goldman', ], [ [['Can you create commerce in order to regulate it', 9]], 'http://yhoo.it/GSgtu8', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/7/78/778e2416573870cd705774e92403447d.jpeg', '630', ' ', 'AP/Charles Dharapak', ], [ [['associated with such a small earthquake', 4]], 'http://yhoo.it/GTco9z', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/0/b4/0b493c1a47b6e3f97f8f48a2b251d7d4.jpeg', '630', ' ', 'AP Photo/Carrie Antlfinger', ], [ [['Fox News host Geraldo Rivera sparked outrage', 3]], 'http://yhoo.it/GKMVTk', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/2/7c/27c7367bc512d233ae1790b320a5e92c.jpeg', '630', ' ', 'AP Photo/John Minchillo', ], [ [['The charges signed against Bales include', 1]], 'http://yhoo.it/wZT5zV', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/7/a0/7a07c51b2aa0f39b1a23355046d13870.jpeg', '512', ' ', 'AP Photo/DVIDS\, Spc\. Ryan Hallock\, File', ], [ [['George Zimmerman, if I had a son', 6]], 'http://news.yahoo.com/photos/thousands-protest-fla-teen-death-1332387124-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/os/152/2012/03/22/d761a49f3fcc99080a0f6a70670053cd-jpg_150905.jpg', '500', ' ', 'AP Photo/John Minchillo', ], [ [['Mohamed Merah', 10], ['prosecutor Francois Molins', 5]], 'http://news.yahoo.com/photos/four-dead-in-french-jewish-school-shooting-1332173151-slideshow', 'Click image to see more photos', 'http://l.yimg.com/cv/ip/ap/default/120321/2012_03_21t151508z_425380421_gm1e83l1sqs01_rtrmadp_3_france_shootings_raid.jpg', '630', ' ', 'REUTERS/Jean-Paul Pelissier', ], [ [['Shortly after he wrapped up his victory remarks', 2]], 'http://news.yahoo.com/photos/4-straight-romney-wins-washington-gop-caucus-1330835515-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/3/e9/3e9b0082c3c3111dcc19e3527ae94cc7.jpeg', '500', ' ', 'AP Photo/Steven Senne', ], [ [['best understands the problems of average Americans', 2]], 'http://news.yahoo.com/photos/4-straight-romney-wins-washington-gop-caucus-1330835515-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/3/e9/3e9b0082c3c3111dcc19e3527ae94cc7.jpeg', '500', ' ', 'AP Photo/Steven Senne', ], [ [['Group for Historic Aircraft Recovery', 7]], 'http://yhoo.it/GB2RVy', 'Click image to see more photos', 'http://l.yimg.com/os/152/2012/03/20/photo-1332257995646-4-0-jpg_171722.jpg', '630', ' ', 'AFP', ], [ [['xxxxxxxxxxxx', 11]], 'http://news.yahoo.com/photos/russian-grannies-win-bid-to-sing-at-eurovision-1331223625-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/1/56/156d92f2760dcd3e75bcd649a8b85fcf.jpeg', '500', ' ', 'AP', ] ]

[ [ [['measure all but certain to fail in the face of bipartisan', 4]], '28771014', '0' ], [ [['matter what you do in this case', 5]], '28759848', '0' ], [ [['presume laws are constitutional', 7]], '28747556', '0' ], [ [['has destroyed 15 to 25 houses', 7]], '28744868', '0' ], [ [['short answer is yes', 7]], '28746030', '0' ], [ [['opportunity to tell the real story', 7]], '28731764', '0' ], [ [['entirely respectable way to put off the searing constitutional controversy', 7]], '28723797', '0' ], [ [['point of my campaign is that big ideas matter', 9]], '28712293', '0' ], [ [['As the standoff dragged into a second day', 7]], '28687424', '0' ], [ [['French police stepped up the search', 17]], '28667224', '0' ], [ [['Seeking to elevate his candidacy back to a general', 8]], '28660934', '0' ], [ [['The tragic story of Trayvon Martin', 4]], '28647343', '0' ], [ [['Karzai will get a chance soon to express', 8]], '28630306', '0' ], [ [['powerful storms stretching', 8]], '28493546', '0' ], [ [['basic norm that death is private', 6]], '28413590', '0' ], [ [['songwriter also saw a surge in sales for her debut album', 6]], '28413590', '1', 'Watch music videos from Whitney Houston ', 'on Yahoo! Music', 'http://music.yahoo.com' ], [ [['keyword', 99999999999999999999999]], 'videoID', '1', 'overwrite-pre-description', 'overwrite-link-string', 'overwrite-link-url' ] ]

university of alabama national championship game bcs game college football college football ncaa football brian van gorder

BUILD YOUR SELF ESTEEM, A STARTER GUIDE TO SELF ...

So how do you stay calm banner stands , composed and preserve self esteem in a troublesome surroundings? Listed here are some suggestions you might to think about as a starter information to self improvement.

Think about yourself as a Dart Board. All the pieces and everybody else round you might turn out to be Dart Pins, at one point or another. These dart pins will destroy your self esteem and pull you down in ways you received?t even remember. Don?t let them destroy you, or get the very best of you. So which dart pins must you avoid?

Dart Pin 1 : Unfavourable Work Setting
Beware of ?canine eat canine? principle the place everybody else is preventing just to get ahead. That is the place non-appreciative people usually thrive. No one will recognize your contributions even if you happen to miss lunch and dinner, and stay up late. Most of the time you get to work an excessive amount of without getting help from people concerned. condos for sale in toronto Keep out of this, it?ll ruin your self esteem. Competition is at stake anywhere. Be healthy sufficient to compete, however in a healthy competitors that is.

Dart Pin 2: Different Individuals?s Behavior
Bulldozers, brown nosers, gossipmongers, whiners, backstabbers, snipers, people walking wounded, controllers, naggers, complainers, exploders, patronizers, sluffers? all these varieties of individuals will pose dangerous vibes in your self esteem, as well as to your self enchancment scheme.

Dart Pin 3: Changing Setting
You may?t be a inexperienced bug on a brown field. Modifications problem our paradigms. It assessments our flexibility, adaptability and alters the best way we think. Modifications will make life tough for awhile, it could cause stress however it?ll help us discover ways to enhance our selves. Change might be there eternally, we must be prone to it.

Dart Pin four: Previous Kitchen sinks Private sellers looking to upgrade, these sellers are those who have outgrown their current, boat agnd agre loogking to buy something bigger. Expertise
It?s okay to cry and say ?ouch!? after we experience pain. But don?t let ache rework itself into fear. It?d grab you by the tail and swing you around. Treat each failure and mistake as a lesson.

Dart Pin 5: Unfavourable World View
Have a look at what you?re trying at. Don?t wrap yourself up with all the negativities of the world. In constructing self esteem, we should learn to make the very best out of worst situations.

Dart Pin 6: Dedication Concept
The way in which you might be and your behavioral traits is alleged to be a mixed finish product of your inherited traits (genetics), your upbringing (psychic), and your environmental surroundings akin to your partner, the corporate, the financial system or your circle of friends. You might have your individual identity. In case your father is a failure, it doesn?t mean you need to be a failure too. Learn from other people?s experience, so that you?ll never have to encounter the same mistakes.

Typically, you might need to wonder if some persons are born leaders or constructive thinkers. NO. Being constructive, and staying constructive is a choice. Building self esteem and drawing lines for self enchancment is a alternative, not a rule or a talent. God wouldn?t come down from heaven and inform you ?George, you might now have the permission to construct self esteem and improve your self.?

In life, its laborious to stay tough specially when issues and other people round you retain pulling you down. After we get to the battle field, we should choose the appropriate baggage to bring and armors to use, and pick these which are bullet proof. Life?s options give us arrays of extra options. Alongside the battle, we will get hit and bruised. And carrying a bullet proof armor ideally means ?self change?. The form of change which comes from within. Voluntarily. Armor or Self Change changes 3 issues: our angle, our conduct and our way of thinking.

Building self esteem will ultimately result in self enchancment if we begin to turn out to be liable for who we?re, what we have and what we do. Its like a flame that ought to step by step unfold like a brush hearth from inside and out. After we develop self esteem, we take management of our mission, values and discipline. Self-worth brings about self enchancment, true assessment, and determination. So how do you begin placing up the constructing blocks of self esteem? Be positive. Be contented and happy. Be appreciative. By no means miss a chance to compliment. A constructive way of living will help you build self esteem, your starter information to self improvement.

obama open mic jefferson county colorado extenze tenacious d steve smith zou bisou bisou tim tebow press conference

Ethics committee: Sen. Vitter of Louisiana violated public trust in blocking Salazar salary (Star Tribune)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories News, News Feeds and News via Feedzilla.

rock and roll hall of fame erin andrews erin andrews blagojevich sentence mythbusters cannonball uss arizona myth busters

Charlie Sheen Apologizes for "Cringeable" Behavior

When Today viewers tuned in this morning, they may have thought they were experiencing a flashback to a year ago. There, sitting opposite Matt Lauer, was a manic, fidgety Charlie Sheen. Between compulsive sips of coffee, he answered questions with jokes and big smiles. He seemed over-caffeinated. Watch the clip here:

rpi dst friends with kids pacific standard time northern mariana islands summer time coolio

Friday, March 30, 2012

Passive approach begins to gain currency ? Financial Times | Forex ...

Passive approach begins to gain currency
Financial Times
While ETFs have proved popular vehicles to gain passive exposure to equities, bonds and commodities, currency is something of a late comer to the party and it is only recently that exchange traded products (ETPs) offering exposure to the asset class ...

and more??

Both comments and pings are currently closed.

Source: http://forexo.tk/passive-approach-begins-to-gain-currency-financial-times/

whitney houston whitney houston autopsy results obama trayvon jim yong kim michael bush the host trailer whitney houston cause of death

Japan bees cook enemy in 'hot defensive bee ball'

TOKYO | Thu Mar 29, 2012 2:41pm EDT

TOKYO (Reuters) - Don't mess with Japanese honeybees. Not only do they cooperate to attack their enemies, researchers now say their brains may actually be processing and responding to the threat.

When confronted with their arch-enemy, the aggressive giant Asian hornet, the honeybees will attack it by swarming en masse around the hornet and forming what scientists call a "hot defensive bee ball" - a move unique to their species.

With up to 500 bees all vibrating their flight muscles at once, the bee ball cooks the hornet to death.

While this defensive maneuver has been known for some time, the mechanism behind it has been shrouded in mystery. But researchers at Japan's University of Tokyo, through study of the bees' brains, have now found that neural activity in bees taking part in the attack picks up.

"When the hornet, the Japanese honeybee's natural enemy, enters a colony, the bees quickly form a 'hot defensive bee ball,' trapping the hornet inside and heating it up to 46 degrees C (115 F) with their collective body heat," said Atsushi Ugajin, a University of Tokyo graduate student.

He said that while the high temperature phase lasts about 20 minutes, it often takes up to an hour before the hornet dies inside the ball.

Set off if bees posted as "guards" at the entrance to the colony detect an intruder, the move evolved because the bee's stingers aren't strong enough to penetrate the hornet's tough exo-skeleton, researchers said.

The research team, whose latest research on the phenomenon appeared in the scientific journal PLoS ONE in mid-March, was astounded by the fact that the collective heat generated by the group, while fatal for the hornet, leaves the bees unaffected.

They were also surprised that the bees used perfectly coordinated teamwork during the process, said Takeo Kubo, a professor at the University of Tokyo graduate school.

"When an outsider enters, the honeybees are immediately on their guard. Then, all at once, they gather to attack," he said.

"So, it isn't one commanding all the rest, we believe in this moment of emergency they're acting collectively."

Curious about why the bees attack this way, the researchers examined their brains and found that neural activity increased in the bees involved with the bee ball, apparently reflecting processing of thermal stimuli.

The group also said that while this discovery may seem to demonstrate that the Japanese honeybee is "smarter" than its European counterpart, this is not the case - it's merely a matter of development in response to environmental factors.

"When a member of the colony, a worker drone, is killed, this is a grievous loss for the hive. Evolution has reacted in this way (for their survival)," said Masato Ono, a Japanese honeybee and hornet expert who was also part of the study.

And many fundamental unknowns remain.

"One of the great mysteries for us is how animals' brains have evolved and how they operate," Kubo said. "This will be for us the next great puzzle to examine."

(Editing by Elaine Lies and Ron Popeski)

Source: http://feeds.reuters.com/~r/reuters/scienceNews/~3/-AWL1f9mhZk/us-japan-bees-idUSBRE82S0AZ20120329

the perfect storm trisomy wwe royal rumble leon panetta luck sag awards 2012 nominees sag awards

Thursday, March 29, 2012

Legal Scholarship Blog: 2012 Lavender Law Conference Call for ...

Call for proposals for the 2012 Lavender Law Conference?hosted by the?National LGBT Bar Foundation?at the Washington Hilton in Washington, D.C.? If you are interested in being a presenter, you can submit a workshop proposal by visiting: Submit a CLE Workshop Proposal. ?Submissions are due by Monday, April 2, at 5:00pm ET (incomplete proposals will not be considered).


Each year, the Lavender Law Conference provides a challenging and rewarding learning experience for attendees and presenters. In addition to day-long seminars focused on family law and transgender issues, the 2012 conference will feature dozens of continuing legal education (CLE) workshops on cutting edge legal issues affecting LGBT individuals, their families and the community. Topics covered in recent years include marriage equality, HIV/AIDS, immigration, LGBT issues in criminal law, LGBT youth issues and many others.

The 2012 conference will also feature workshops geared specifically towards corporate counsel and business practitioners. Topics in previous years included intellectual property, outsourcing and globalization, best practices for winning business from clients interested in LGBT diversity, employment law issues from both the management and plaintiffs? perspective and others. Distinguished speakers for the 2012 Lavender Law Conference will include representatives from Wells Fargo, Kellogg, Bank of America, Starbucks, Microsoft and many more! mb

Posted by uwlegalscholarship on March 29th, 2012 | Business Law, CALLS FOR PAPERS, Civil Rights Law, CONFERENCES, Labor and Employment Law, Law and Gender, Law and Sexuality | no comments

No comments yet.

Source: http://legalscholarshipblog.com/2012/03/29/2012-lavender-law-conference-call-for-papers-washington-d-c/

maria menounos proposition 8 ricky martin chauncey billups caucus results exton red dawn

Arab summit to stop short of call for Assad ouster

[ [ [['A JetBlue flight from New York to Las Vegas', 3]], 'http://yhoo.it/GV9zpj', '[Related: View photos of the JetBlue plane in Amarillo]', ' ', '630', ' ', ' ', ], [ [['Afghan security forces and police killed three', 3]], 'http://yhoo.it/H9BcJE', '[Related: Bales\' wife on his alleged shooting: \'He would not do that\']', ' ', '630', ' ', ' ', ], [ [['looking for fireworks between the opposing camps', 16]], 'http://yhoo.it/GSvEsj', '[RELATED:\?It?s going to be a circus\?: Activists begin protests outside Supreme Court]', ' ', '630', ' ', ' ', ], [ [['entirely respectable way to put off the searing constitutional controversy', 8]], 'http://yhoo.it/GE6jSh', '[RELATED: Obama\?s health care law passed 2 years ago, but where are we now\?]', ' ', '630', ' ', ' ', ], [ [['Witnesses said the gunman pulled up on a black scooter', 7]], 'http://yhoo.it/GzwOIW', '[Related: New York police tighten security at Jewish sites]', ' ', '630', ' ', ' ', ], [ [['test Zimmerman for alcohol or drugs', 11]], 'http://yhoo.it/Gzn6VF', '[Related: White House says Trayvon Martin is local issue]', ' ', '630', ' ', ' ', ], [ [['Trayvon Martin decked the Neighborhood', 7]], 'http://yhoo.it/GUovUP', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/2/61/261d2c36bccf0971c2734a4d4398aa5a.jpeg', '512', ' ', 'AP/David Goldman', ], [ [['Can you create commerce in order to regulate it', 9]], 'http://yhoo.it/GSgtu8', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/7/78/778e2416573870cd705774e92403447d.jpeg', '630', ' ', 'AP/Charles Dharapak', ], [ [['associated with such a small earthquake', 4]], 'http://yhoo.it/GTco9z', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/0/b4/0b493c1a47b6e3f97f8f48a2b251d7d4.jpeg', '630', ' ', 'AP Photo/Carrie Antlfinger', ], [ [['Fox News host Geraldo Rivera sparked outrage', 3]], 'http://yhoo.it/GKMVTk', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/2/7c/27c7367bc512d233ae1790b320a5e92c.jpeg', '630', ' ', 'AP Photo/John Minchillo', ], [ [['The charges signed against Bales include', 1]], 'http://yhoo.it/wZT5zV', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/7/a0/7a07c51b2aa0f39b1a23355046d13870.jpeg', '512', ' ', 'AP Photo/DVIDS\, Spc\. Ryan Hallock\, File', ], [ [['George Zimmerman, if I had a son', 6]], 'http://news.yahoo.com/photos/thousands-protest-fla-teen-death-1332387124-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/os/152/2012/03/22/d761a49f3fcc99080a0f6a70670053cd-jpg_150905.jpg', '500', ' ', 'AP Photo/John Minchillo', ], [ [['Mohamed Merah', 10], ['prosecutor Francois Molins', 5]], 'http://news.yahoo.com/photos/four-dead-in-french-jewish-school-shooting-1332173151-slideshow', 'Click image to see more photos', 'http://l.yimg.com/cv/ip/ap/default/120321/2012_03_21t151508z_425380421_gm1e83l1sqs01_rtrmadp_3_france_shootings_raid.jpg', '630', ' ', 'REUTERS/Jean-Paul Pelissier', ], [ [['Shortly after he wrapped up his victory remarks', 2]], 'http://news.yahoo.com/photos/4-straight-romney-wins-washington-gop-caucus-1330835515-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/3/e9/3e9b0082c3c3111dcc19e3527ae94cc7.jpeg', '500', ' ', 'AP Photo/Steven Senne', ], [ [['best understands the problems of average Americans', 2]], 'http://news.yahoo.com/photos/4-straight-romney-wins-washington-gop-caucus-1330835515-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/3/e9/3e9b0082c3c3111dcc19e3527ae94cc7.jpeg', '500', ' ', 'AP Photo/Steven Senne', ], [ [['Group for Historic Aircraft Recovery', 7]], 'http://yhoo.it/GB2RVy', 'Click image to see more photos', 'http://l.yimg.com/os/152/2012/03/20/photo-1332257995646-4-0-jpg_171722.jpg', '630', ' ', 'AFP', ], [ [['xxxxxxxxxxxx', 11]], 'http://news.yahoo.com/photos/russian-grannies-win-bid-to-sing-at-eurovision-1331223625-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/1/56/156d92f2760dcd3e75bcd649a8b85fcf.jpeg', '500', ' ', 'AP', ] ]

[ [ [['matter what you do in this case', 5]], '28759848', '0' ], [ [['presume laws are constitutional', 7]], '28747556', '0' ], [ [['has destroyed 15 to 25 houses', 7]], '28744868', '0' ], [ [['short answer is yes', 7]], '28746030', '0' ], [ [['opportunity to tell the real story', 7]], '28731764', '0' ], [ [['entirely respectable way to put off the searing constitutional controversy', 7]], '28723797', '0' ], [ [['point of my campaign is that big ideas matter', 9]], '28712293', '0' ], [ [['As the standoff dragged into a second day', 7]], '28687424', '0' ], [ [['French police stepped up the search', 17]], '28667224', '0' ], [ [['Seeking to elevate his candidacy back to a general', 8]], '28660934', '0' ], [ [['The tragic story of Trayvon Martin', 4]], '28647343', '0' ], [ [['Karzai will get a chance soon to express', 8]], '28630306', '0' ], [ [['powerful storms stretching', 8]], '28493546', '0' ], [ [['basic norm that death is private', 6]], '28413590', '0' ], [ [['songwriter also saw a surge in sales for her debut album', 6]], '28413590', '1', 'Watch music videos from Whitney Houston ', 'on Yahoo! Music', 'http://music.yahoo.com' ], [ [['keyword', 99999999999999999999999]], 'videoID', '1', 'overwrite-pre-description', 'overwrite-link-string', 'overwrite-link-url' ] ]

Source: http://news.yahoo.com/arab-ministers-debate-syria-draft-resolution-041911061.html

super bowl 2012 kickoff time football score ron paul nevada buffalo chicken dip super bowl 2012 soul train nevada caucus

Wednesday, March 28, 2012

Deborah Cox to join 'Jekyll & Hyde' in 2013

In this May 18, 2010 photo, Singer Deborah Cox arrives for the World Music Awards, in Monaco. Dr. Jekyll and Mr. Hyde have their love interest, Deborah Cox. Producers of the Broadway-bound revival of "Jekyll & Hyde" announced Tuesday, March 27, 2012, that the Grammy Award nominated singer will join Constantine Maroulis in the musical that's slated to come to New York in spring 2013 after a 25-week national tour that starts in San Diego on Oct. 2. (AP Photo/Mark Mainz)

In this May 18, 2010 photo, Singer Deborah Cox arrives for the World Music Awards, in Monaco. Dr. Jekyll and Mr. Hyde have their love interest, Deborah Cox. Producers of the Broadway-bound revival of "Jekyll & Hyde" announced Tuesday, March 27, 2012, that the Grammy Award nominated singer will join Constantine Maroulis in the musical that's slated to come to New York in spring 2013 after a 25-week national tour that starts in San Diego on Oct. 2. (AP Photo/Mark Mainz)

NEW YORK (AP) ? Dr. Jekyll and Mr. Hyde have found their love interest ? Deborah Cox.

Producers of the Broadway-bound revival of "Jekyll & Hyde" announced Tuesday that the Grammy-nominated singer will join Constantine Maroulis in the musical that's slated to come to New York in spring 2013 after a 25-week national tour that starts in San Diego on Oct. 2,

Cox, who sang the lead role in Elton John and Tim Rice's Broadway musical "Aida," has had six top 20 Billboard R&B singles, including the smash "Nobody's Supposed To Be Here."

Maroulis, who was a finalist on the fourth season of "American Idol," has been in "Rock of Ages" and received a best actor Tony nomination for his performance.

___

Online: http://www.JekyllandHydeMusical.com

Kennebec Journal

Source: http://hosted2.ap.org/APDEFAULT/4e67281c3f754d0696fbfdee0f3f1469/Article_2012-03-27-Theater-Jekyll%20and%20Hyde/id-386b8845c2ce4380a3f7d00c2d14299e

kurt warner kurt warner ricky williams missouri primary minnesota caucus knowshon moreno knowshon moreno

AMP optimistic in suit to invalidate patents on breast cancer genes

AMP optimistic in suit to invalidate patents on breast cancer genes [ Back to EurekAlert! ] Public release date: 27-Mar-2012
[ | E-mail | Share Share ]

Contact: Mary Steele Williams
mwilliams@amp.org
301-634-7921
Association for Molecular Pathology

Bethesda, MD -- Now that the Supreme Court has remanded Association for Molecular Pathology et al. v. Myriad Genetics, Inc., et al. (AMP v. Myriad) to the Court of Appeals for the Federal Circuit for further consideration, AMP is optimistic that it will ultimately prevail in its lawsuit to invalidate patents on two genes that are known to cause breast cancer.

"Our members have witnessed the adverse effects of gene patents on patient care," stated Iris Schrijver, AMP President. "By awarding monopolies in testing of patented genes, these patents reduce patient access to genetic tests, increase test prices, and stand in the way of innovations in diagnostic methods." Further, Dr. Schrijver added, "Because variation in gene sequences plays an important role in the development and progression of many diseases, through gene patents patent holders can essentially gain ownership of the understanding of some diseases and of certain areas of patient care itself."

Stated Roger D. Klein, MD, JD, Chair of the AMP Professional Relations Committee: "We were extremely encouraged by the Supreme Court's reaffirmation in its Prometheus decision of the longstanding principle that natural phenomena are not patent eligible. In Prometheus, the Supreme Court clearly ruled that the correlation between a biomarker and a clinical phenotype cannot be patented. Similarly, in light of this decision we expect that the Court of Appeals for the Federal Circuit will ultimately find that patents on natural products, in this case BRCA1 and BRCA2, cannot be used to exclude physicians and others from examining their patient's genes for disease-related variants."

In its original decision, the Appeals Court held that human gene sequences are patentable subject matter when separated from their native state within cells. This is really a 'form versus substance' argument, said Mary Williams, AMP Executive Director. "A disease-causing mutation means the same thing for the patient irrespective of whether a gene is examined inside or outside the patient's body."

"AMP is looking forward to the proceedings in the lower court. We are confident that optimal patient care and sound science will ultimately prevail," stated Williams.

###

ABOUT AMP:

The Association for Molecular Pathology (AMP) is an international medical professional association dedicated to the advancement, practice, and science of clinical molecular laboratory medicine and translational research based on the applications of molecular biology, genetics, and genomics. For more information, please visit www.amp.org.



[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


AMP optimistic in suit to invalidate patents on breast cancer genes [ Back to EurekAlert! ] Public release date: 27-Mar-2012
[ | E-mail | Share Share ]

Contact: Mary Steele Williams
mwilliams@amp.org
301-634-7921
Association for Molecular Pathology

Bethesda, MD -- Now that the Supreme Court has remanded Association for Molecular Pathology et al. v. Myriad Genetics, Inc., et al. (AMP v. Myriad) to the Court of Appeals for the Federal Circuit for further consideration, AMP is optimistic that it will ultimately prevail in its lawsuit to invalidate patents on two genes that are known to cause breast cancer.

"Our members have witnessed the adverse effects of gene patents on patient care," stated Iris Schrijver, AMP President. "By awarding monopolies in testing of patented genes, these patents reduce patient access to genetic tests, increase test prices, and stand in the way of innovations in diagnostic methods." Further, Dr. Schrijver added, "Because variation in gene sequences plays an important role in the development and progression of many diseases, through gene patents patent holders can essentially gain ownership of the understanding of some diseases and of certain areas of patient care itself."

Stated Roger D. Klein, MD, JD, Chair of the AMP Professional Relations Committee: "We were extremely encouraged by the Supreme Court's reaffirmation in its Prometheus decision of the longstanding principle that natural phenomena are not patent eligible. In Prometheus, the Supreme Court clearly ruled that the correlation between a biomarker and a clinical phenotype cannot be patented. Similarly, in light of this decision we expect that the Court of Appeals for the Federal Circuit will ultimately find that patents on natural products, in this case BRCA1 and BRCA2, cannot be used to exclude physicians and others from examining their patient's genes for disease-related variants."

In its original decision, the Appeals Court held that human gene sequences are patentable subject matter when separated from their native state within cells. This is really a 'form versus substance' argument, said Mary Williams, AMP Executive Director. "A disease-causing mutation means the same thing for the patient irrespective of whether a gene is examined inside or outside the patient's body."

"AMP is looking forward to the proceedings in the lower court. We are confident that optimal patient care and sound science will ultimately prevail," stated Williams.

###

ABOUT AMP:

The Association for Molecular Pathology (AMP) is an international medical professional association dedicated to the advancement, practice, and science of clinical molecular laboratory medicine and translational research based on the applications of molecular biology, genetics, and genomics. For more information, please visit www.amp.org.



[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2012-03/afmp-aoi032712.php

mitch hedberg welcome back kotter 2001 a space odyssey barefoot bandit polar bear plunge lovelace antioch

Sunday, March 25, 2012

How to Teach Your Child Healthy Fitness Habits | Natural Holistic ...

If you enjoy this post, please share it using the buttons in the post, or email it to a friend, we'd really appreciate it!

There was a time when kids just kind of kept themselves in shape; overweight kids were the exception. Nowadays, however, with childhood obesity on the rise, parents, teachers, and caregivers are all finding it necessary to implement fitness programs and encourage fit lifestyles for kids.

So how can you teach your child healthy fitness habits that will stay with them for a lifetime? Here are some ideas.

Participation

Let your kids in on your fitness routine. (Don?t have one? There?s the first step ? implement one!) Have them come along on your morning walk or run, or let them do a workout video with you. It might take some time to get them integrated, but it introduces them to the concept of regular workouts and the idea that exercise is fun. This also puts you in the position of positive role model for your kids.

Playtime = Fitness Time

Children are naturally playful. Engaging in free play is one of the best ways to encourage them to get in shape and develop healthy habits. Toddlers like to dance and be active at all kinds of play, as do preschoolers. Older kids may enjoy playing sports or just running races with their friends.

If it?s snowing, get the kids to go outside and play in it; in the fall, rake leaves into piles and jump in. Spring and summer provide all kinds of outdoor possibilities. The point is to deliberately integrate active play time into your child?s day.

Make the Time

Because we tend to expect fitness to come naturally to kids, many families neglect to schedule it in. But these days, that?s an important step. Make sure your kids have the time to be active and move around. Sometimes, we spend a lot of our day telling our children to be still, be quiet, pay attention, and so forth. Try to schedule in some time when your child can be physically active.

Playgrounds

Playgrounds exist for a reason ? play! Make it a point to take your child to a playground several times a week. Make playdates with other moms and kids if you like, and make it a regular thing. When the weather gets bad, see if you can continue your habit in an indoor play area, community center gym, or church fellowship hall.

Family Sports

Signing your kids up for sports is a great idea, but if your child is the shy type, he or she may benefit more from family sports. Also, if the family participates, it encourages Mom and Dad to exercise, too.


Free PDF Health Ebook...

Special Report: What Our Skin Tells Us About our Health

? ? Simply right click the ebook title above, and choose Save As to save to your desktop!? You can find more FREE Natural Health, Wellness and Pet Ebooks at Remedies4.com!


Source: http://www.natural-holistic-health.com/how-to-teach-your-child-healthy-fitness-habits/

vanessa bryant nfl mock draft 2012 adam lambert incendiary floyd mayweather winter solstice x factor finale

Republicans Liked McCain More Than Romney, Santorum and Gingrich

[ [ [['Witnesses said the gunman pulled up on a black scooter', 7]], 'http://yhoo.it/GzwOIW', '[Related: New York police tighten security at Jewish sites]', ' ', '630', ' ', ' ', ], [ [['test Zimmerman for alcohol or drugs', 11]], 'http://yhoo.it/Gzn6VF', '[Related: White House says Trayvon Martin is local issue]', ' ', '630', ' ', ' ', ], [ [['Fox News host Geraldo Rivera sparked outrage', 3]], 'http://yhoo.it/GKMVTk', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/2/7c/27c7367bc512d233ae1790b320a5e92c.jpeg', '630', ' ', 'AP Photo/John Minchillo', ], [ [['The charges signed against Bales include', 1]], 'http://yhoo.it/wZT5zV', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/7/a0/7a07c51b2aa0f39b1a23355046d13870.jpeg', '512', ' ', 'AP Photo/DVIDS\, Spc\. Ryan Hallock\, File', ], [ [['George Zimmerman, if I had a son', 6]], 'http://news.yahoo.com/photos/thousands-protest-fla-teen-death-1332387124-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/os/152/2012/03/22/d761a49f3fcc99080a0f6a70670053cd-jpg_150905.jpg', '500', ' ', 'AP Photo/John Minchillo', ], [ [['Mohamed Merah', 10], ['prosecutor Francois Molins', 5]], 'http://news.yahoo.com/photos/four-dead-in-french-jewish-school-shooting-1332173151-slideshow', 'Click image to see more photos', 'http://l.yimg.com/cv/ip/ap/default/120321/2012_03_21t151508z_425380421_gm1e83l1sqs01_rtrmadp_3_france_shootings_raid.jpg', '630', ' ', 'REUTERS/Jean-Paul Pelissier', ], [ [['Shortly after he wrapped up his victory remarks', 2]], 'http://news.yahoo.com/photos/4-straight-romney-wins-washington-gop-caucus-1330835515-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/3/e9/3e9b0082c3c3111dcc19e3527ae94cc7.jpeg', '500', ' ', 'AP Photo/Steven Senne', ], [ [['best understands the problems of average Americans', 2]], 'http://news.yahoo.com/photos/4-straight-romney-wins-washington-gop-caucus-1330835515-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/3/e9/3e9b0082c3c3111dcc19e3527ae94cc7.jpeg', '500', ' ', 'AP Photo/Steven Senne', ], [ [['Group for Historic Aircraft Recovery', 7]], 'http://yhoo.it/GB2RVy', 'Click image to see more photos', 'http://l.yimg.com/os/152/2012/03/20/photo-1332257995646-4-0-jpg_171722.jpg', '630', ' ', 'AFP', ], [ [['xxxxxxxxxxxx', 11]], 'http://news.yahoo.com/photos/russian-grannies-win-bid-to-sing-at-eurovision-1331223625-slideshow/', 'Click image to see more photos', 'http://l.yimg.com/a/p/us/news/editorial/1/56/156d92f2760dcd3e75bcd649a8b85fcf.jpeg', '500', ' ', 'AP', ] ]

[ [ [['As the standoff dragged into a second day', 7]], '28687424', '0' ], [ [['French police stepped up the search', 17]], '28667224', '0' ], [ [['Seeking to elevate his candidacy back to a general', 8]], '28660934', '0' ], [ [['The tragic story of Trayvon Martin', 4]], '28647343', '0' ], [ [['Karzai will get a chance soon to express', 8]], '28630306', '0' ], [ [['powerful storms stretching', 8]], '28493546', '0' ], [ [['basic norm that death is private', 6]], '28413590', '0' ], [ [['songwriter also saw a surge in sales for her debut album', 6]], '28413590', '1', 'Watch music videos from Whitney Houston ', 'on Yahoo! Music', 'http://music.yahoo.com' ], [ [['keyword', 99999999999999999999999]], 'videoID', '1', 'overwrite-pre-description', 'overwrite-link-string', 'overwrite-link-url' ] ]

Source: http://news.yahoo.com/republicans-liked-mccain-more-romney-santorum-gingrich-221000793.html

84th annual academy awards beginners 2012 oscars the shore meryl streep oscar wins sasha baron cohen oscars oscar winners

Saturday, March 24, 2012

News and results from Merseyside and Cheshire golf scene

FIVE local players have been named in the Lancashire Boys team to take part in the Four Counties competition at West Lancashire.

The eight-strong team includes James Rooney and Louis Tomlinson from the host club.

Joining them at the Crosby links will be Sean Blinkhorne (Southport and Ainsdale), Ian Stirling (Formby) and England squad member Haydn McMullen (Delamere Forest).

The rest of the team for the tournament ? which takes place from April 2-4 ? is Sami Procter-Bouzabia (Preston), Joey Lamb (Wilpshire) and Ben Richards (Pike Fold).

ADAM Powell turned up the heat in the fourth Mansell Finishes Winter Series Pro-am with a seven birdie spree at Royal Liverpool.

The 28-year-old Hartford professional reeled off four in the opening eight holes on his way to posting an impressive five under par 67 to beat David Shacklady by a shot.

And the PGA Cup player from Mossock Hall had to settle for second spot in the team prizes by the same margin as Powell enjoyed a double pay day with clubmate Mal Wells.

LEADING SCORES (Par 72): 67 Adam Powell (Hartford); 68 David Shacklady (Mossock Hall); 70 Steve Parry (NW Golf Academy), Simon Edwards (Windermere)

ANNE Baines (Royal Birkdale), the county training officer for Lancashire Ladies, has been invited to serve on the England Golf Coaching Committee.

It is one of the five new committees formed following the merger of the English Golf Union and the English Women?s Golf Association to help run the amateur game in England.

RESULTS

CHESHIRE UNION

Boys pre-season meeting (at Warrington GC): Gross, 1st Josh Garside (Prestbury) 38pts; 2nd, Mathew Myers (Sandiway) 35 Best Nett: Jack Duncalf (Sandiway) 39

HELSBY

Team Texas Scramble: 1st, Val Pritchard, Pam Thompson, Lesley McClusky 50.5; 2nd, Marion Moss, Ruth Metcalfe, June Cunniffe 50.8

CARDEN PARK

The Wynn Royle Mixed Trophy: 1st, Nigel Dick/Jill Harper; 2nd, Mike Goodwin/Anna James; 3rd, Dave Cooper/Helen Groves

CHESTER

Lady Captain's Drive In (11 hole Am/Am): 1st, Pat Willis, Pauline Gurney, Noreen Nickson, Helen Jones 44pts; 2nd, Sheila Banham, Sheila Watson, Elizabeth Jones, Les Kirby 43; 3rd, Judith Foden, Ellen Walton, Chris Skellon, Patsy Baker 42

VICARS CROSS

Lady Captain?s Charity: Silver Div, winner Joyce Alsop 35pts (cpo); runner-up, Julia Heritage 35 Bronze A, winner, Jen Leech 38; runner-up, Deb Davies 36 Bronze B, winner Jenny Hunt 33; runner-up, Carol Harvey 30

'); tm.siteLife.daapi.getArticle( "21-99623-30593131", function(article){ tm.siteLife.display.displayCommentCount( article, 'sitelife-commentsWidget-middle', false, 'Comments', true, false ); } ); })();//call anonymous function //]]>

Source: http://www.liverpooldailypost.co.uk/sport/community-sport/2012/03/22/news-and-results-from-merseyside-and-cheshire-golf-scene-99623-30593131/

prometheus trailer patrice oneal shamrock slainte the quiet man yellow cab dropkick murphys

Personal Finance: Tax Refunds to be Spent En Masse this Year ...

According to Capital One Bank, most Americans who receive a tax refund will promptly spend it in some form or fashion this year. The average refund, which has been estimated at $2,913, will go in many cases to ?everyday expenses? (28 percent), while another 28 percent of those surveyed plan to make a major purchase like electronics, a vacation, or new clothing and accessories[1]. A little less than a third of those surveyed reported a plan to save ?at least part of the money,? however, while 17 percent anticipated paying down a debt and five percent intended to invest the funds.

Interestingly, 69 percent of all Americans do not calculate their tax refund or tax payment into their annual budget, the survey showed. And those who owe taxes do not appear to be planning ahead much either. Only 25 percent have money set aside specifically for taxes, while 19 percent will work out a payment plan with the IRS. 32 percent will pay up front, but will have to dip into personal savings to do so. [2]?Tax season is a good opportunity for people to plan ahead,? one financial planner pointed out, adding that tax refunds represent ?a good opportunity for people to plan ahead with an eye toward their future goals and financial health.? This is the second year in a row that this survey has indicated that a third or more of Americans plan to spend part or all of their refund.

How do you handle tax season? Does this survey reflect your tax habits?

Thank you for reading the Bryan Ellis Investing Letter!

Your comments and questions are welcomed below.


[1] http://www.bankinvestmentconsultant.com/news/Most-Americans-Plan-to-Spend-Their-Tax-Refunds-2677966-1.html

[2] http://www.marketwatch.com/story/a-third-of-americans-plan-to-spend-all-or-part-of-their-tax-refund-finds-capital-one-bank-survey-2012-03-20

Category: Financial Markets, Real Estate, Retirement Planning

Source: http://investing.bryanellis.com/1351/personal-finance-tax-refunds-to-be-spent-en-masse-this-year/

kirkwood chris brown and rihanna nightline brady quinn brady quinn bloom box fat tuesday

Friday, March 23, 2012

American Idol Power Poll: The Top 10


With the American Idol top 10 taking the stage again tonight, and with this shaping up to be one of the more hotly-contested seasons to date, it's time for the first THG Power Poll of the season.

Who do you see as the favorite right now?

American Idol Top 10

10. Deandre Brackensick: Would have been our choice to leave after last week's debacle. He can hit the high notes... and that's about it.

9. Heejun Han: Love the personality, don't see anything on stage that makes him standout above the rest. It's solid and nothing more or less.

8. Elise Testone: Might suffer some likability issues. Did you notice her NOT applauding for Erika last week? Or not hugging Skylar? Yes, we're forced to nitpick when the talent is this even. We did love her version of "Let's Stay Together."

7. Joshua Ledet: We expect plenty of disagreement here. It's not a question of his voice, just of his theatrics. Ledet's "When a Man Loves a Woman" may have been the single best of any contestant this season, but we can see his act growing old.

6. Skylar Laine: She has the energy and the attitude, that's for sure. She also has the identity: a rocking country chick. She just lacks the range.

5. Erika Van Pelt: Loved her take on“Edge of Glory." A smooth, consistent voice makes it hard to see this finalist faltering in the next few weeks.

4. Colton Dixon: Love the risks he takes - a song by White Lion?!? - and love his confidence on stage. Most definitely stands out on a weekly basis.

3. Jessica Sanchez: Will go down in Idol history for her version of “I Will Always Love You." That should be enough to keep her around for awhile. But can she go outside the world of ballads? A less-than-impressive take on “Turn the Beat Around" causes us to wonder.

2. Hollie Cavanagh: Has she had an off week yet? Memorable auditions of “Reflection,” “All the Man That I Need,” and “The Power of Love" prove she has staying power. Could work on her versatility and stage presence.

1. Phillip Phillips: He's a cute young white guy with a guitar. Until American Idol viewers prove they are capable of crowning someone else, he has to be the favorite.

WHO IS YOUR AMERICAN IDOL FAVORITE?

Source: http://www.thehollywoodgossip.com/2012/03/american-idol-power-poll-the-top-10/

music awards giants eagles bcs rankings week 13 bcs rankings week 13 philadelphia marathon rhodes scholar cranberry sauce recipe

Thursday, March 22, 2012

Why Web Hosting is Important to Social Media Management | Corbie ...

Social media management wouldn?t have a branch to stand on if it wasn?t for web hosting; the same thing goes for online reputation management. In fact if it wasn?t for web hosting the internet in general would cease to exist. The global markets would fall; teenagers and adults wouldn?t know what to do with their lives; phones would have no function; it would be the end of the world as we know and love it if Web hosting was suddenly gone.

Web hosting is a type of Digital hosting service that allows individuals and organizations to make their own website accessible via the World Wide Web. Basically, all the websites that we consider and love have a web hosting service so that we can visit them in our on-line world. If they weren?t there, the websites themselves wouldn?t be backed up and could leave; no to mention that we, the people surfing the web, wouldn?t be able to get on the site anyway.

The reason this is important to social media management and reputation management is because they, like the rest of the world now-a-days, use the internet to achieve business; and without web hosting they wouldn?t be able to. Don?t believe me? Let?s start with web marketing then. Web marketing, like its name suggests, is any action taken to market a web site or company online including web site promoting, search engine submission, pay-per-click advertising and traffic analysis. Now, marketing, without the web element, can use other means then just the internet to conduct business. But ?Web Marketing,? focuses solely on marketing using the internet, which requires websites that would not exist without web hosting services.

Social media management has a similar dependency on the internet and ergo web hosting. Social media management is the individual in an organization creditworthy with monitoring, contributing to, filtering, measuring and otherwise guiding the social media presence of a brand, product, individual or corporation. Their role is similar to that of a community manager on a website forum or public relations representative. Now, social media management can function without the internet, they can act like public relations spokesperson, but since most businesses use the internet as a base to do business in today?s business market, they job would be gravely inconvenienced without the internet and Web hosting.

So next time you looking up the latest offerings and bargains on the internet, don?t take it for granted. Everything on the internet is interdependent and if one part of that fragile cyber ecosystem suddenly dies; so will all the rest.

fishbat is a web web marketing agency that can help you with marketing and social media management. Check out fishbat.com. This article, Why Web Hosting is Important to Social Media Management has free reprint rights.

Source: http://main.corbiehosting.com/2012/03/22/why-web-hosting-is-important-to-social-media-management/

us geological survey oklahoma fall back when does daylight savings start when does daylight savings start earthquake in texas earthquake in texas

Structure of ?salvia? receptor solved

ScienceDaily (Mar. 21, 2012) ? At the molecular level, drugs like salvinorin A (the active ingredient of the hallucinogenic plant Salvia divinorum) work by activating specific proteins, known as receptors, in the brain and body.

Salvinorin A, the most potent naturally occurring hallucinogen, is unusual in that it interacts with only one receptor in the human brain -- the kappa opioid receptor (KOR). Scientists know of four distinct types of opioid receptors, but until now the structure of the 'salvia receptor', and the details about how salvinorin A and other drugs interact with it, was a mystery.

In a research paper published March 21 in the journal Nature, scientists from the University of North Carolina at Chapel Hill, Scripps Research Foundation and two other institutions revealed the first-ever glimpse of the complete structure of the KOR. The finding could accelerate the development of new drugs to treat addiction, depression, anxiety, chronic pain and many other conditions.

"Once we see the structure of the receptor, it becomes easier for us to develop drugs that target the receptor in ways that might be beneficial for medical therapy," said Bryan Roth, MD, PhD, the Michael Hooker Distinguished Professor of Pharmacology at UNC and one of the paper's authors. "Drugs that block the receptor are potentially useful for treating a number of serious illnesses including chronic pain, cocaine addiction and other diseases."

The KOR is responsible for the action of drugs that affect human consciousness, awareness of pain and mood. The KOR is the only receptor that binds salvinorin A -- the active ingredient of the widely-abused hallucinogenic plant Salvia divinorum (also known as 'Magic mint', 'Salvia' and so on). Salvia use has surged among teenagers and young adults with more than 5 percent reporting usage in the past year.*

Knowing KOR's structure offers insights about how salvia and other drugs work. The finding also could help scientists design medicines that either activate or block KOR to benefit patients.

The research team crystallized KOR using JDTic, a drug currently in early-stage human trials; JDTic keeps KOR in an inactive state and blocks the actions of salvinorin A. In studies using animal models, JDTic has shown promise for treating cocaine and nicotine addiction, depression and anxiety.

The downside of JDTic and similar drugs targeting KOR is that they can exert their actions for weeks, whereas most prescribed medicines are cleared within 18-24 hours. "Now that we have the [KOR] structure, it opens up the possibility for us to make drugs that have the same action as JDTic but have better pharmaceutical properties," said Roth.

The research also resolves longstanding scientific debates about how drugs bind to KOR. The study found that compared to other receptors, the binding site on KOR is enormous, allowing drugs to bind to it in more than one way.

In addition, Roth said the research could help scientists develop drugs that activate KOR in the body without affecting the brain, which could be useful for treating chronic pain, kidney problems and many other disorders.

Co-authors include Eyal Vardy and Xi-Ping Huang at UNC-Chapel Hill; Huixian Wu, Daniel Wacker, Vsevolod Katritch, Mauro Mileni, Gye Won Han, Wei Liu, Aaron A. Thompson, Vadim Cherezov and Raymond C. Stevens from the Scripps Research Institute; F. Ivy Carroll and S. Wayne Mascarella from the Research Triangle Institute; and Richard B. Westkaemper and Philip D. Mosier from Virginia Commonwealth University.

The study was supported by funding from the National Institutes of Health.

* Source: National Institute on Drug Abuse InfoFacts; http://www.drugabuse.gov/publications/infofacts/salvia.

Share this story on Facebook, Twitter, and Google:

Other social bookmarking and sharing tools:


Story Source:

The above story is reprinted from materials provided by University of North Carolina at Chapel Hill School of Medicine, via Newswise.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Huixian Wu, Daniel Wacker, Mauro Mileni, Vsevolod Katritch, Gye Won Han, Eyal Vardy, Wei Liu, Aaron A. Thompson, Xi-Ping Huang, F. Ivy Carroll, S. Wayne Mascarella, Richard B. Westkaemper, Philip D. Mosier, Bryan L. Roth, Vadim Cherezov, Raymond C. Stevens. Structure of the human ?-opioid receptor in complex with JDTic. Nature, 2012; DOI: 10.1038/nature10939

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://www.sciencedaily.com/releases/2012/03/120321142018.htm

unc asheville stephen jackson nba trade deadline cbs ncaa tournament peyton hillis marchmadness

Wednesday, March 21, 2012

Ways to Copy Wii system Games Effortlessly ? Typically the ...

2012
03.20

This isn?t very tough to imitate the Wii console games it is possible to the right style of doing thus.

It doesn?t make a change which how to rip wii games system you have, this strategy is often put directly into use for just about any of these. No make a difference whether question XBOX, XBOX, Wii and / or all three ones, they may all turn out to be duplicated successfully. So, why don?t you just develop a backup from your original into a clear disc and additionally use the fact that instead.

You find, the copyright laws protection the fact that Nintendo with this Wii is easy.

Video activities have a variety of copyright guards fitted which reduces ordinary copying software applications from using up them. First of, insert a groundbreaking disc into your DVD-ROM get.

Have you bought a Wii gaming console and would like to see how to backup cds? It?s an effective possibility for you to solely copy a existing cadre connected with video ISOs to protect yourself from have an effect on them or and prevent becoming them nicked. First and additionally foremost detail is you should insert a original Wii console game game. ?If everyone still enjoy the mature games, also you can copy games belonging to the oldest game consoles, that include:,? smiling celebrated author Megan Hanson indicated. The biggest advantage to make sure you creating file backup copies from your Nintendo Wii console games is you do not need to care about the genuine games getting damaged. You may well only own one performance system today, yet you do not know precisely what is going to occur, so you might get equipped by having a program that can backup every games.

o Download the solution which must decode the sport disc and additionally allows this transfer of this contents to a new disc. As an important console, the Nintendo wii gaming console is full of the exact same problems as the various other competitions products which is that subsequent to repeated use the hard disks containing the unique games certainly deteriorate.

Tags: how to make copies of wii games

Source: http://boatswain.info/ways-to-copy-wii-system-games-effortlessly-typically-the-effortless-approaches-to-burn-wii-system-games/

alcs alcs pay it forward pay it forward haunted houses favicon.ico favicon.ico

Robin's Roundup

Last Wednesday, March 14, voting opened for the 5th Annual Children's Choice Book Awards here. This program is the only one of its kind. First, in 4 of the 6 categories (Book of the Year for 4 different age groups beginning with Kindergarteners and ending with teens), kids and teens select the finalists. Approximately 20,000 kids and teens from across the country participate in the part of the program. To select the Author of the Year and Illustrator of the Year finalists we review bestseller lists. Second, this is a national program where kids and teens select the winners. Votes have already been submitted by participants in every state in the country (and beyond). We are expecting to receive one million votes this year.

The program was developed 5 years ago by the Children's Book Council and the literacy foundation Every Child a Reader for a number of reasons.

  • It makes reading fun and gives kids an easy way to talk about their favorite books with their friends - yes, it makes talking about books fun for kids.?
  • It gives kids and teens a chance to express themselves and let book creators know what works best for them and what they love most.?
  • Because the majority of finalists are selected by kids and teens, it offers a peer-approved reading list.
  • It is an essential component of the strategy developed to instill a lifelong love of reading in young people, the mission of Every Child a Reader
If you have children in your life, please encourage them to participate in the amazing program. Read with them and ask them about their preferences. If the child in your life is a teen who has no desire to share preferences with you at the moment, consider reading what he or she is reading or read the Teen Book of the Year finalists and get a sense of what moves other teens. It might help you find a conversation starter. So get started. Click here to see the finalists and start reading!

Beginning tomorrow, each post (and, yes, for those of you doubters, there will be posts to come) will tie one of the thirty finalists to a parent/child issue or story until I've covered them all.

The winners of the Children's Choice Book Awards program, by the way, will be announced live at a gala event on May 7 in New York City that will officially kick off Children's Book Week 2012. The 5th Annual gala will be hosted by the award-winning and beloved creator of the Lunch Lady series of graphic novels (not to mention Punk Farm, Ollie and so many more!), Jarrett J Krosoczka. Awards will be presented by iconic authors and illustrators like Marc Brown (Arthur), Mary Pope Osborne (Magic Tree House), Andrew Clements (Frindle) and S.E. Hinton (The Outsiders), Jack Gantos (Dead End in Norvelt) and Chris Raschka (A Ball for Daisy). An Impact award will be presented by National Ambassador for Young People?s Literature Walter Dean Myers to Super Bowl Champion New York Giants? Justin Tuck in recognition of the important work he has done connecting kids and books through his charity, Tuck?s R.U.S.H. for Literacy.? It will be an evening of champions! A video of the awards presentation will be available on May 8 so remember to tune into the Children's Book Week website to see it almost live if you can't be there in person.

Rest well, my friends, for tomorrow we start the marathon of Children's Choice Book Awards reading!

Source: http://robinadelson.blogspot.com/2012/03/last-wednesday-march-14-voting-opened.html

sweet caroline lottery winning numbers pro bowl roster quirky chrissy teigen chia seeds embers

Kingston DataTraveler R500


While USB flash drives are getting faster, sometimes what you really want is simply more capacity. The Kingston DataTraveler R500 ($200 street) may not be the fastest flash drive around, limited as it is to USB 2.0 instead of 3.0, but it is certainly one of the largest, offering a whopping 128GB of storage space. Wrap it all in a rugged, moisture-resistant enclosure, and you've got a storage device that's ready to go just about anywhere.

Design and Features
The DataTraveler R500 is a high-capacity flash drive about the size of a Bic lighter. A two-toned black and orange color scheme makes it highly visible, and a tether point on the back of the drive makes it easy to attach to a key ring or lanyard. Measuring 0.5 by 0.9 by 2.8 inches (HWD), the R500 may crowd out neighboring ports, but it's still fairly slim and weighs only 1 ounce.

The rubber housing provides protection against the hazards of everyday life, from dropping your keys on the floor to leaving your drive in your pocket as it goes through the laundry. The drive also has a slight tapering from front to back, and the back end is narrow enough that the cap can be slipped over the end when the drive is in use.

The drive comes preformatted to FAT32, meaning that it is ready to go out of the box on virtually any system, whether it's a Windows, Mac, or Linux machine. There's also no extraneous software included, so you get nothing but uncluttered storage, without the hassles of setting up a password or dealing with management software.

Offering a hefty 128GB of storage space, the DataTraveler R500 sells for $1.56 per gigabyte. Though it sells for a higher overall price, this is a lower cost per GB than is offered by other high-capacity drives, like the USB 3.0-based Kingston DataTraveler Ultimate 3.0 Generation 2 (32GB) ($80 street, 4 stars) ($2.35 per GB) or the Corsair Flash Voyager GT ($64.99 direct, 4 stars) ($2.03 per GB).

Performance
Though it couldn't run PCMark 7, the DataTraveler R500 still produced decent read and write speeds, with read speeds of 30 MBps and write speeds of 21 MBps. While these numbers can't match the blazing fast speeds offered by USB 3.0 drives, they still represent tolerable performance from a USB 2.0 drive with so much storage capacity.

The biggest thing that the DataTraveler R500 has going for it is that it's just that?big. 128GB is a lot of storage space, and while that capacious storage might be faster accessed with a USB 3.0 connection, there's still plenty to be said about having that much storage space on hand wherever you go. It also benefits from a rugged rubber housing, so your files and photos will be well protected.

COMPARISON TABLE
Compare the Kingston DataTraveler R500 with several other flash drives side by side.

More flash drive reviews:
??? Corsair Flash Voyager GT (32GB)
??? Corsair Flash Voyager USB 3.0
??? Kingston DataTraveler Ultimate 3.0 Generation 2 (32GB)
??? Kingston DataTraveler Locker+ (8GB)
??? Victorinox Swiss Army Slim Flight
?? more

Source: http://feedproxy.google.com/~r/ziffdavis/pcmag/~3/16sCdkrtsEA/0,2817,2401650,00.asp

josh powell madonna halftime show linsanity the alamo north korea news north korea news anencephaly

Tuesday, March 20, 2012

Home Improvement | Electric Fireplace?Your Home Needs One ...

Home improvement and enhancement is always something worth investing on. If you want to stay comfortable and safe around your home, of course you would only want to own what?s best out there in the market. Fireplaces are famous for their extensive capabilities when it comes to decorating a home and making it even more comfortable during the cold seasons.
There?s a huge assortment of fireplaces in the market today and one of the most convenient and safest to use is the electric fireplace. This hearth is not just only for warming up your home, but it is also one of the best room enhancement unit you could ever own. Unlike central heating systems you have for your home, electrical hearths can even make your home look very regal and warm at the same time. They come in many different styles and sizes, thus you can definitely find one that perfectly fits your living room, bedroom, dining room, and office.
Electrical hearths can give out an expensive and luxurious feel to your home. However, these hearths are not at all very expensive. Because of their great features, they are much more on reasonably priced units. Imagine you get a wonderful d?cor and warmer from one unit.
Installation of electrical hearths will need the expertise of a licensed electrician. This is because, electrical hearths will need a dedicated circuit to make sure that it provides the correct amount of energy while being used. Almost all models of modern electrical hearths are now like plug-and-play style. This means that as soon as you plug it, it is now ready to use. A remote controlled electric hearth can even let you experience a very convenient way of warming up your home. The remote can provide you quick access to several heat adjustments and also the color flames.
Electrical hearths are even useful during the warm months. This is because they also include another special feature that lets you turn on the beautiful flames without the heat. As a result, you get a soothing ambiance anytime you like. When you are having guest around, it?s nice to gather them around in a room where your beautiful electrical hearth can be the focal point. It will definitely make wonderful scenery for everybody.
An electric fireplace will bring a wonderful atmosphere to your home. Unlike gas fireplaces an traditional ones, you don?t get to experience getting bad fumes and toxic smoke around your home.
Article Source:?http://www.bharatbhasha.net
Article Url: http://www.bharatbhasha.net/home_improvement.php/356547

Article Added on Tuesday, March 20, 2012
LD

Other Articles by Mary Jone

?Safely and Stylishly Enjoy Your Nightly Blazes with an Electric Fireplace
On wintry nights, there is nothing better to do than to sit before a warm fireplace. Yet, some fireplaces are very hard to operate and can even pose a lot of risks. Surely, in your quest for a safer system, you wouldn't want to sacrifice the beauty of your sought-after hearth. Thus, if you wish to safely and stylishly enjoy your nightly blazes at home during cold and chilly season, then you should opt into using an electric fireplace. An electric fireplace is safe to use because it doesn't...

?Electric Fireplaces For A Satisfying Warmth And Ambient Atmosphere
The convenience and ease of use that electric fireplaces have to offer is undeniable. They are mainly designed to provide good warmth during the cold months without the troubles of chopping wood or purchasing fuels. They are available in huge assortments of style from freestanding to wall mounted. An electrical hearth is equipped with a heating stove. When the unit is plugged to a dedicated circuit, energy is then converted to heat which is then absorbed by the coils of the stove. As the coils...

Source: http://www.bharatbhasha.net/home_improvement.php/356547

trick or treat times trick or treat times madoff bernie madoff anna chapman kim kardashian honda generator